An Antigenic Fraction of the Lymphosarcoma 6C3HED of the C3H Mouse1
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چکیده
Antigenic components were solubilized from a participate fraction of mouse lymphosarcoma 6C3HED at pH 9.0-9.5. Protein, lipid, and carbohydrate were present. Three measures of antigenicity were employed. Mouse cytotoxicity tests re vealed that the tumor fraction adsorbed a greater amount of rabbit antitumor antibody than did similar fractions of normal C3H mouse lymphoid tissues. In Schultz-Dale tests, prior desensitization of immune C3H mouse uterine muscle with spleen and lymph node-thymus antigens did not eliminate a response to the tumor antigens. The immunization of C3H mice by a single injection of the tumor antigenic preparation in Freund's complete adjuvant resulted in a greater number
منابع مشابه
An antigenic fraction of the lymphosarcoma 6C3HED of the C3H mouse.
Antigenic components were solubilized from a participate fraction of mouse lymphosarcoma 6C3HED at pH 9.0-9.5. Protein, lipid, and carbohydrate were present. Three measures of antigenicity were employed. Mouse cytotoxicity tests re vealed that the tumor fraction adsorbed a greater amount of rabbit antitumor antibody than did similar fractions of normal C3H mouse lymphoid tissues. In Schultz-Dal...
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